Tetrahydrofuran → 2,6-dichloro-N-(3-fluorobenzyl)-4-methyl-pyridine-3-carboxylic acid amide

HRID 92400Notes

Reaction equation

HRID 92400 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([CH3:11])[c:7]1[C:8](=[O:9])[OH:10].[F:13][c:14]1[cH:15][c:16]([CH2:17][NH2:18])[cH:19][cH:20][cH:21]1.[P-:22]([F:23])([F:24])([F:25])([F:26])([F:27])[F:28].[n:29]1([O:30][C:31]([N:32]([CH3:33])[CH3:34])=[N+:35]([CH3:36])[CH3:37])[c:38]2[n:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([CH3:11])[c:7]1[C:8](=[O:10])[NH:18][CH2:17][c:16]1[cH:15][c:14]([F:13])[cH:21][cH:20][cH:19]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 9886HexafluorophosphateHCID 668533-FluorobenzylamineHCID 6761212,6-Dichloro-4-methylpyridine-3-carboxylic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 866643132,6-dichloro-N-(3-fluorobenzyl)-4-methyl-pyridine-3-carboxylic acid amide

Sources & evidence

ORD record
ord-2ea653f5ac24448f8eb502c535a9948b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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