反应详情

A solution of 1-ethenyl-4-(trifluoromethyl)benzene (1.72 mL, 11.6 mmol) in THF (60 mL) was stirred in the presence of Pd/C (10%, 400 mg), under a hydrogen atmosphere (45 psi) for 7 h. The solid was filtered through celite (washed with DCM) and the filtrate was carefully concentrated, keeping the temperature of the bath below 20° C. at 200 mmHg. The concentrated solution thus obtained was used in the next step without further manipulation.

1. filtrationThe solid was filtered through celite (washed with DCM)
2. concentrationthe filtrate was carefully concentrated
3. customthe temperature of the bath below 20° C.
4. customThe concentrated solution thus obtained