2-Aminothiophenol → HCID 68549937, compound

HRID 925149Notes

Reaction equation

HRID 925149 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[CH3:9][N:10]([CH3:22])[C:11]1[CH:18]=[CH:17][C:14]([CH:15]=O)=[C:13]([N+:19]([O-:21])=[O:20])[CH:12]=1>>[S:8]1[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[N:1]=[C:15]1[C:14]1[CH:17]=[CH:18][C:11]([N:10]([CH3:9])[CH3:22])=[CH:12][C:13]=1[N+:19]([O-:21])=[O:20]

Participants

3

Reactant 2

HCID 87132-AminothiophenolHCID 2913524-Dimethylamino-2-nitrobenzaldehyde

Product 1

HCID 68549937HCID 68549937, compound

Procedure

The amine may be obtained, for example in analogy to methods described in DE-A-2333378. For example, the educts 2-aminothiophenol and 4-dimethylamino-2-nitrobenzaldehyde may be reacted to obtain (4-benzothiazol-2-yl-3-nitrophenyl)-dimethylamine, whose nitro group may be reduced to the amine in a conventional manner (e.g. using SnCl2/HCl), and the product is reacted with methane sulfochloride.

Sources & evidence

ORD record
ord-12ecdd6a98fc462caa48707d068d46f0
Source dataset
uspto-grants-2016_03
Patent number
US09284278B2

Reaction notes

Loading…