Potassium Carbonate → HCID 66558345, compound

Participants

Reaction Steps

50 mg (0.155 mmol) of 1-tert-butyl-5-[2-(methylsulfonyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxamide were dissolved in 1.5 mL of dry DMF; then, 30 mg (0.17 mmol) of 4-piperazin-1-yl-phenol and 64 mg (0.464 mmol) of potassium carbonate were added. The final suspension was stirred at 70° C. for 1 h then the final mixture was purified by preparative HPLC/MS to provide the title compound (20%).

Provenance & Evidence