HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride → 4-Cyclopropyl-thiazole-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride | HCID 57578796 | — |
| Reactant | Lithium 4-cyclopropylthiazole-2-carboxylate | HCID 68792487 | — |
| Product | 4-Cyclopropyl-thiazole-2-carbonyl chloride | HCID 59434826 | — |
Reaction Steps
Compound 267a was synthesized from compound 266a (3 g, 1 eq.) as a brown solid in quantitative yield, following the procedure as described for compound 214. MS (ESI, EI+): m/z=170 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284307B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-55a82b560cde458ebfd38cb2e38cd7f2 |
| Source note | uspto-grants-2016_03 |