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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 92665Generated: October 27, 2026

Tetrahydrofuran → 2-(4-bromo-2-fluoroanilino)-N-[2-[tert-butyl(dimethyl)silyl]oxypropoxy]-1-methyl-6-oxopyridine-3-carboxamide

https://huagongshe.com/reaction/92665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
ReactantO-[2-[tert-butyl(dimethyl)silyl]oxypropyl]hydroxylamineHCID 21111571—
ReactantMethyl 2-(4-bromo-2-fluorophenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylateHCID 66673525—
Product2-(4-bromo-2-fluoroanilino)-N-[2-[tert-butyl(dimethyl)silyl]oxypropoxy]-1-methyl-6-oxopyridine-3-carboxamideHCID 87100918—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-a9f32995f4cd44548136461dffdfcd81
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)