Lithium iodide → HCID 117902180, compound

Participants

Reaction Conditions

Reaction Steps

3,15-Dioxa-tricyclo[11.3.0.0*2,4*]hexadecane from Step 1 (260 g, 1.16 mol) was mixed with lithium iodide (2.5 g, 18.7 mmol) and heated to 200° C. for 8 hours. The reaction was then cooled down and washed with water (500 mL). The crude was distilled to provide dodecahydro-2-oxa-cyclopentacyclododecen-4-one (138 g, ˜53% yield).

Provenance & Evidence