HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 926707Generated: November 1, 2026
Hydrochloric Acid → HCID 89618838, compound
https://huagongshe.com/reaction/926707
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 89618808 | HCID 89618808 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 89618838 | HCID 89618838 | — |
Reaction Steps
(R)-4-((tert-butoxycarbonyl)amino)-1-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyridine-3-carbonyl)piperidine-4-carboxylic acid (100 mg, 0.17 mmol) added to 4N HCl in Dioxane (5 mL) was stirred at 20-35° C. for 3 h. The reaction mixture was concentrated under reduced pressure to afford crude. The crude obtained was washed with diethyl ether and dried to afford 58 mg of the title compound as a pale brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09289419B2 |
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| Source dataset | uspto-grants-2016_03 |
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| ORD ID | ord-45309b96f2764ca5b96a8f5e544318f8 |
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| Source note | uspto-grants-2016_03 |
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