反应详情

温度

25 °C

2-fluoro-5-nitropyridine (30 g, 18.9 mmol) was added to a stirred solution of 1H-1,2,4-triazole (1.566 g, 22.7 mmol) and K2CO3 (5.14 g, 37.8 mmol) and stirred for 16 hrs at 25° C. Reaction mass was diluted with ice cold water and stirred for 15 min. The solid obtained was filtered and dried under vacuum to afford the desired product. MS (ESI): m/z 192 (M+H).

1. customReaction mass
2. additionwas diluted with ice cold water
3. stirringstirred for 15 min
4. customThe solid obtained
5. filtrationwas filtered
6. customdried under vacuum