HCID 90203466, compound → HCID 76071554, compound

Participants

Reaction Steps

4-[4-(4-tert-Butoxycarbonylamino-isoxazol-3-yl)-phenoxymethyl]-benzoic acid methyl ester was suspended in 4N hydrochloric acid in dioxane (20 volumes) and stirred at rt for 16 hours (reaction progress monitored by TLC). The solvent was removed by evaporation to give 4-[4-(4-amino-isoxazol-3-yl)-phenoxymethyl]-benzoic acid methyl ester as the hydrochloride salt, which required no further purification. M+1=325.2

Provenance & Evidence