HCID 90203161, compound → HCID 74763821, compound

Participants

Reaction Steps

{3-[4-(4-Methanesulfonyl-benzyloxy)-phenyl]-isoxazol-4-yl}-carbamic acid tert-butyl ester (20.5 mg, 0.046 mmol) was dissolved in a 2M HCl in dioxanes (5 mL, 10 mmol) and stirred at rt until no starting material remained. Removal of volatiles under reduced pressure and workout according to Example 2 provided 3-[4-(4-methanesulfonyl-benzyloxy)-phenyl]-isoxazol-4-ylamine (14.5 mg, 91%). HRMS (M+1)=345.09

Provenance & Evidence