Hydrochloric Acid → HCID 76071680, compound

Participants

Reaction Steps

{3-[4-(2-Oxo-2-phenyl-ethoxy)-phenyl]-isoxazol-4-yl}-carbamic acid tert-butyl ester (70 mg, 0.18 mmol) was dissolved in dioxane (1 mL) and treated with 4N HCl in dioxane (1 mL, 4 mmol). After stirring overnight the resulting white solid was removed by filtration and washed with hexanes to yield 2-[4-(4-Amino-isoxazol-3-yl)-phenoxy]-1-phenyl-ethanone hydrochloride as a white solid (34 mg, 64%). MH+=295.0

Provenance & Evidence