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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927067Generated: October 26, 2026

1-Ethynyl-3,5-difluorobenzene → 3,4-bis(Benzyloxy)-6-[(3,5-difluorophenyl)ethynyl]pyridazine

https://huagongshe.com/reaction/927067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-3,5-difluorobenzeneHCID 4206806—
Reactant3,4-Bis(benzyloxy)-6-chloropyridazineHCID 12213474—
Reactant3,4-Bis(benzyloxy)-6-(phenylethynyl)pyridazineHCID 71270419—
Product3,4-bis(Benzyloxy)-6-[(3,5-difluorophenyl)ethynyl]pyridazineHCID 71270017—

Reaction Steps

Prepared as described for 3,4-bis(benzyloxy)-6-(phenylethynyl)pyridazine (Intermediate 2) from 3,4-bis(benzyloxy)-6-chloropyridazine (Intermediate 1) and 1-ethynyl-3,5-difluorobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290456B2
Source datasetuspto-grants-2016_03
ORD IDord-a1e1bd7ce6aa4222bbcc1905fa25e1d5
Source noteuspto-grants-2016_03