HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 178424854, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 3,4-Bis(benzyloxy)-6-[2-(3-fluoro-4-methylphenyl)ethynyl]pyridazine | HCID 71270242 | — |
| Reactant | 3-Hydroxy-6-(2-Phenylethyl)pyridazin-4(1h)-One | HCID 178518808 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178424854 | HCID 178424854 | — |
Reaction Steps
Prepared by the same method as for 4-hydroxy-6-(2-phenylethyl)pyridazin-3(2H)-one (Example 1) from 3,4-bis(benzyloxy)-6-[2-(3-fluoro-4-methylphenyl)ethynyl]pyridazine (Intermediate 28) except that the solvent mixture used for the hydrogenation was ethyl acetate and methanol (1:1) and the final product was recrystallised from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290456B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-43267618b00e442ca9f38268303d638f |
| Source note | uspto-grants-2016_03 |