HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71270194, compound → HCID 178518791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71270194 | HCID 71270194 | — |
| Reactant | 3-Hydroxy-6-(2-Phenylethyl)pyridazin-4(1h)-One | HCID 178518808 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178518791 | HCID 178518791 | 46% |
Reaction Steps
Prepared in the same manner as 4-hydroxy-6-(2-phenylethyl)pyridazin-3(2H)-one (Example 1) from 3,4-bis(benzyloxy)-6-(cyclopropylidenemethyl)pyridazine (Intermediate 65) except that methanol was used as the reaction solvent. The crude compound was purified by preparative HPLC to yield 6-(cyclopropylmethyl)-4-hydroxypyridazin-3(2H)-one (46% yield)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290456B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0ad93e610cd94918ac5419ff61c8dccb |
| Source note | uspto-grants-2016_03 |