HCID 13199823, compound → HCID 82125639, compound

HRID 927187Notes

Reaction equation

HRID 927187 reaction equation
[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1.[O:12]1[C:16]2[CH:17]=[CH:18][C:19]([C:21]([CH3:25])([CH3:24])[CH2:22][OH:23])=[CH:20][C:15]=2[O:14][CH2:13]1>C(Cl)Cl>[O:12]1[C:16]2[CH:17]=[CH:18][C:19]([C:21]([CH3:25])([CH3:24])[CH:22]=[O:23])=[CH:20][C:15]=2[O:14][CH2:13]1

Participants

4

Reactant 2

HCID 13199823HCID 13199823, compoundHCID 178418287HCID 178418287, compound2×

Product 1

HCID 82125639HCID 82125639, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A suspension of 3A° molecular sieves (6.5 g) in CH2Cl2 (15 mL) was stirred at room temperature for 30 minutes and then PCC (pyridinium chlorochromate) (2 g) was added. To this PCC suspension, a solution of Compound H (1 g, 5.15 mmol) in dry CH2Cl2 (15 mL) was added dropwise and was stirred at room temperature for 3.5 hours.

Workup

  1. stirringwas stirred at room temperature for 3.5 hours

Sources & evidence

ORD record
ord-8bae8e74a6604d6ba370d9a9ed5b5a0b
Source dataset
uspto-grants-2016_03
Patent number
US09290473B2

Reaction notes

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