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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927294Generated: October 31, 2026

Quinazolinedione → HCID 68388650, compound

https://huagongshe.com/reaction/927294

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinazolinedioneHCID 64048—
ReactantMethyl 5-(bromomethyl)-2-fluorobenzoateHCID 22645461—
ReactantHCID 68388893HCID 68388893—
ProductHCID 68388650HCID 68388650—

Reaction Steps

The title compound was prepared from quinazoline-2,4(1H,3H)-dione and methyl 5-(bromomethyl)-2-fluorobenzoate using a procedure similar to those described for the synthesis of compound of Example 1. 1H NMR (DMSO-d6): 11.75 (s, 1H), 8.00 (d, J=7.8 Hz, 1H), 7.84 (d, J=6.9 Hz, 1H), 7.67-7.55 (m, 2H), 7.32-7.21 (m, 3H), 5.32 (s, 2H), 3.81 (s, 3H). MS: m/z 329.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290460B2
Source datasetuspto-grants-2016_03
ORD IDord-994807d3cd9e4e61b82aad8227f60930
Source noteuspto-grants-2016_03