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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927301Generated: November 1, 2026

6-Fluoroquinazoline-2,4(1H,3H)-dione → HCID 68389141, compound

https://huagongshe.com/reaction/927301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Fluoroquinazoline-2,4(1H,3H)-dioneHCID 16658240—
ReactantMethyl 5-(bromomethyl)-2-fluorobenzoateHCID 22645461—
ReactantHCID 68388893HCID 68388893—
ReactantHCID 68388908HCID 68388908—
ProductHCID 68389141HCID 68389141—

Reaction Steps

The following compounds were prepared from 6-fluoro-1-(3-carboxy-4-fluorobenzyl)quinazoline-2,4(1H,3H)-dione (prepared from 6-fluoroquinazoline-2,4(1H,3H)-dione and methyl 5-(bromomethyl)-2-fluorobenzoate using procedures similar to those of compounds of Examples 1 and 2), and the corresponding substituted piperazine using a procedure similar to those described for the synthesis of compound of Example 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290460B2
Source datasetuspto-grants-2016_03
ORD IDord-1cfb8a532742415cb5d52531db9d08a9
Source noteuspto-grants-2016_03