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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927444Generated: October 27, 2026

6-(3-Chlorophenyl)picolinic acid → 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid ((S)-3-methyl-1-thiazol-2-yl-butyl)-amide

https://huagongshe.com/reaction/927444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3-Chlorophenyl)picolinic acidHCID 24730135—
Reactant(S)-alpha-(2-methylpropyl)-2-thiazolemethanamineHCID 42078239—
Product6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid ((S)-3-methyl-1-thiazol-2-yl-butyl)-amideHCID 71105567—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and (S)-α-(2-methylpropyl)-2-thiazolemethanamine as starting materials, MS (LC/MS): 386.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-ce7a4f24569642db9920abcfbf0ebe0d
Source noteuspto-grants-2016_03