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HRID 927457作成日：2026年10月25日

6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid → 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amide

https://huagongshe.com/reaction/927457

反応式

関与物質

役割名称HCID仕込み量
反応物6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acidHCID 71087599—
反応物6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amideHCID 71105570—
生成物6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amideHCID 71105575—

反応手順

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid (Example 36 d) and (S)-2-cyclopropyl-1-thiazol-2-yl-ethylamine (Example 59 b) as starting materials, MS (LC/MS): 358.2 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09290451B2
出典データセットuspto-grants-2016_03
ORD IDord-049ba77d15744da292ed5e1020a3b358
出典メモuspto-grants-2016_03