HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-N,2-dimethylpropanamide → 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-N,2-dimethylpropanamide | HCID 18792214 | — |
| Reactant | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid | HCID 71087453 | — |
| Product | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide | HCID 71113051 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (Example 48 e) and 2-amino-N,2-dimethyl-propanamide (CAN 106914-07-2) as starting materials, MS (EI) m/e: 372.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-5c49a3666b97493f905b90dc5268c9a5 |
| Source note | uspto-grants-2016_03 |