HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate → 2-Amino-2-ethyl-N-methyl-butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate | HCID 86674754 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Amino-2-ethyl-N-methyl-butyramide | HCID 79810370 | 75% |
Reaction Steps
A mixture of tert-butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate (0.18 g, 0.74 mmol) in 10 ml saturated hydrochloride in ethyl acetate was stirred for 60 min at room temperature. Then the solution was evaporated to dryness to obtain the product (80 mg, 75%) as a light yellow solid; MS (LC/MS): 145.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-573140ff27fb4a91acb1c9cefbce0f74 |
| Source note | uspto-grants-2016_03 |