HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(1,2,4-Oxadiazol-3-yl)propan-2-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-butyl N-[2-(1,2,4-oxadiazol-3-yl)propan-2-yl]carbamate | HCID 73357654 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-(1,2,4-Oxadiazol-3-yl)propan-2-amine hydrochloride | HCID 86674755 | 94% |
Reaction Steps
tert-Butyl 2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamate (0.668 g, 2.9 mmol) was dissolved in in ethyl acetate saturated with hydrochloride (10 mL) and stirred at room temperature for 0.5 h. Then it was concentrated to give product (0.45 g, 94%); MS (EI): m/e=128.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-58a50a08bd0b4c6ca898b831cb44e0af |
| Source note | uspto-grants-2016_03 |