HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 7,7-dimethyl-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)propan-2-yl)-5,6,7,8-tetrahydroquinoline-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine | HCID 43559251 | — |
| Reactant | 7,7-Dimethyl-5,6,7,8-tetrahydro-quinoline-2-carboxylic acid | HCID 71087472 | — |
| Product | 7,7-dimethyl-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)propan-2-yl)-5,6,7,8-tetrahydroquinoline-2-carboxamide | HCID 71087656 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 7,7-dimethyl-5,6,7,8-tetrahydro-quinoline-2-carboxylic acid (Example 143 d) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, LC-MS (UV peak area/EIC) 100%, 329.1977 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9482680e6aa0462cb19b2588d082ce94 |
| Source note | uspto-grants-2016_03 |