돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 927764생성일: 2026년 10월 25일

Ethyl 2-amino-2-ethylbutanoate hydrochloride → Ethyl 2-(6-(cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoate

https://huagongshe.com/reaction/927764

반응식

참여 물질

역할이름HCID투입량
반응물Ethyl 2-amino-2-ethylbutanoate hydrochlorideHCID 24201639—
반응물6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acidHCID 71087457—
생성물Ethyl 2-(6-(cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoateHCID 71087413—

반응 단계

In analogy to the procedure described in Example 293, 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) were condensed to the title product. MS (EI): m/e=403.4 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09290451B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-aaf3a14b277341eaba5f453a92bdd830
출처 메모uspto-grants-2016_03