Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927940Generated: November 3, 2026

Methyl 7-pivalamido-2H-chromene-8-carboxylate → Methyl 4-methyl-7-(tert-butoxycarbonylamino)-2H-chromene-8-carboxylate

https://huagongshe.com/reaction/927940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 7-pivalamido-2H-chromene-8-carboxylateHCID 70983794—
ReactantMethyl 2-[bis-(tert-butyoxycarbonyl)amino]-6-(but-2-ynyloxy)benzoateHCID 90086596—
ProductMethyl 4-methyl-7-(tert-butoxycarbonylamino)-2H-chromene-8-carboxylateHCID 71006962—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 45, starting from methyl 2-[bis-(tert-butyoxycarbonyl)amino]-6-(but-2-ynyloxy)benzoate (Intermediate 54).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-203d07f96e88422faa842656aedde758
Source noteuspto-grants-2016_03