Iodoethane → HCID 53256385, compound

HRID 927978Notes

Reaction equation

HRID 927978 reaction equation
[CH2:1]([N:3]1[CH2:7][CH2:6][C@H:5]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])[CH2:4]1)[CH3:2].N1CC[C@@H](NC(=O)OC(C)(C)C)C1.ICC>>[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])[CH2:4]1)[CH3:2]

Participants

4

Reactant 3

HCID 6340IodoethaneHCID 1514397(3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidineHCID 53256801HCID 53256801, compound

Product 1

HCID 53256385HCID 53256385, compound

Procedure

Prepared by proceeding in a similar manner to intermediate 82, starting from tert butyl (R)-pyrrolidin-3-yl-carbamate and iodoethane as a light coloured gum.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6166026529fb44268a5baa102b43ea09
Source dataset
uspto-grants-2016_03
Patent number
US09290472B2

Reaction notes

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