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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928018Generated: October 30, 2026

tert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylate → (R)-2-(Pyrrolidin-2-yl)acetonitrile hydrochloride

https://huagongshe.com/reaction/928018

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylateHCID 10727173—
Reactant(S)-2-(Pyrrolidin-2-yl)acetonitrile hydrochlorideHCID 86713338—
Product(R)-2-(Pyrrolidin-2-yl)acetonitrile hydrochlorideHCID 86713341—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 138, starting from tert-butyl (R)-2-cyanomethylpyrrolidine-1-carboxylate (Intermediate 144) and used without further characterisation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-ba1b5a73778c47a1b85026918b8ff7f3
Source noteuspto-grants-2016_03