Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928073Generated: October 30, 2026

tert-butyl (S)-3-(2-chlorosulfonyl-5-fluorobenzyloxy)pyrrolidine-1-carboxylate → tert-butyl (R)-3-(2-chlorosulfonyl-5-fluorobenzyloxy)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/928073

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (S)-3-(2-chlorosulfonyl-5-fluorobenzyloxy)pyrrolidine-1-carboxylateHCID 86713368—
Reactanttert-butyl (R)-3-(2-bromo-5-fluorobenzyloxy)pyrrolidine-1-carboxylateHCID 86713373—
Producttert-butyl (R)-3-(2-chlorosulfonyl-5-fluorobenzyloxy)pyrrolidine-1-carboxylateHCID 86713372—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 215, starting from tert-butyl (R)-3-(2-bromo-5-fluorobenzyloxy)pyrrolidine-1-carboxylate (Intermediate 220).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-a6341dde41574808bf994451aef537cf
Source noteuspto-grants-2016_03