HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → Phosphonium, [(3-fluorophenyl)methyl]triphenyl-, bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3-Fluorobenzyl bromide | HCID 68007 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Phosphonium, [(3-fluorophenyl)methyl]triphenyl-, bromide | HCID 10527583 | 84.6% |
Reaction Steps
A mixture of 3-fluorobenzyl bromide (5 g) and triphenyl phosphine (6.94 g) in toluene (50 mL) was heated at reflux for 3 hours. After cooling, the solid was collected by filtration, washed with toluene and dried under vacuum at 50° C. to give (3-fluorobenzyl)triphenylphosphonium bromide (10.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290472B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-3d2b5c4e47394095b44286b0654be188 |
| Source note | uspto-grants-2016_03 |