反应详情

A mixture of 3-fluorobenzyl bromide (5 g) and triphenyl phosphine (6.94 g) in toluene (50 mL) was heated at reflux for 3 hours. After cooling, the solid was collected by filtration, washed with toluene and dried under vacuum at 50° C. to give (3-fluorobenzyl)triphenylphosphonium bromide (10.1 g).

1. temperaturewas heated
2. temperatureat reflux for 3 hours
3. temperatureAfter cooling
4. filtrationthe solid was collected by filtration
5. washwashed with toluene
6. customdried under vacuum at 50° C.