反应详情

To a solution of tert-butyl 3-(9-isopropyl-6-((1-methyl-1H-pyrazol-4-yl)amino)-9H-purin-2-yl)piperidine-1-carboxylate (620 mg) in DCM (15 mL) was added TFA (1.2 mL). The resulting solution was stirred at ambient temperature for 1 hr. The volatiles were removed to give the crude title compound that was used in the next step without further purification.

1. customThe volatiles were removed