(S)-4-(8-Amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide → Acalabrutinib

Beteiligte Stoffe

Reaktionsschritte

This compound was prepared, in an analogous manner as described in Example 2, from the compound described in intermediate 2b and 2-butynoic acid, to afford the title compound (10.5 mg, 18.0%). Data: LCMS (B) Rt: 2.08 min; m/z 466.1 (M+H)+.

Herkunft & Nachweise