Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928714Generated: October 26, 2026

4-Fluorobenzaldehyde → 5-(4-Fluorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione

https://huagongshe.com/reaction/928714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant2-(4-Chlorobenzyl)malonic acidHCID 2785145—
Reactant5-(4-Chlorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dioneHCID 10880110—
Product5-(4-Fluorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dioneHCID 86096352—

Reaction Steps

The title compound was prepared using 4-fluorobenzaldehyde in place of 4-chlorobenzaldehyde using the procedure described for the preparation of 5-(4-chlorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (Intermediate 3: step a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290476B2
Source datasetuspto-grants-2016_03
ORD IDord-d4b06cda4f33488fb6d53e919145d34f
Source noteuspto-grants-2016_03