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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928731Generated: November 1, 2026

2-(Thiophen-2-ylmethyl)propanedioic acid → HCID 86715588, compound

https://huagongshe.com/reaction/928731

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Thiophen-2-ylmethyl)propanedioic acidHCID 236591—
Reactant6-Bromo-2,4-dichloro-3-(4-chlorobenzyl)quinolineHCID 86715580—
ProductHCID 86715588HCID 86715588—

Reaction Steps

The title compound was prepared by substituting 2-(4-chlorobenzyl)malonic acid (Intermediate 3: step b) with 2-(thiophen-2-ylmethyl)malonic acid (Intermediate 9: step b) then following the procedure described for the preparation of 6-bromo-2,4-dichloro-3-(4-chlorobenzyl)quinoline (Intermediate 3: step c).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290476B2
Source datasetuspto-grants-2016_03
ORD IDord-f5b8694512814168a5a802e982ada1ed
Source noteuspto-grants-2016_03