HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminum hydride → HCID 12306526, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminum hydride | HCID 14487 | — |
| Reactant | 3,4-diphenyl-5H-furan-2-one | HCID 344049 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 12306526 | HCID 12306526 | — |
Reaction Steps
After dissolving compound 18 (1.00 g, 4.23 mmol) in THF (20 ml), the temperature was reduced to or and DIBAL-H (12.96 ml) was dropped. After the agitation for 3 hours was carried out, the reaction was terminated and the extraction was conducted with EA. The organic layer was washed five times with brine and the column chromatography was carried out to obtain compound 19.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296690B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-173e62e61415495ea087ff4833a31c92 |
| Source note | uspto-grants-2016_03 |