HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Bis-trifluoromethylphenylboronic acid → 5-(tert-Butyl)-2-hydroxy-3',5'-bis(trifluoromethyl)-[1,1'-biphenyl]-3-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Bis-trifluoromethylphenylboronic acid | HCID 156265 | — |
| Reactant | 3-Bromo-5-tert-butyl-2-hydroxybenzaldehyde | HCID 7172096 | — |
| Reactant | 5-(Tert-butyl)-2-hydroxy-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carbaldehyde | HCID 86718719 | — |
| Product | 5-(tert-Butyl)-2-hydroxy-3',5'-bis(trifluoromethyl)-[1,1'-biphenyl]-3-carbaldehyde | HCID 86718722 | — |
Reaction Steps
5-(tert-Butyl)-2-hydroxy-3′,5′-bis(trifluoromethyl)-[1,1′-biphenyl]-3-carbaldehyde was prepared as an orange oil using the procedure described in Intermediate 5 from 3-bromo-5-(tert-butyl)-2-hydroxybenzaldehyde (Intermediate 4) and 3,5-bis(trifluoromethyl)phenylboronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296696B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-53bff7d414754882be592c501770568b |
| Source note | uspto-grants-2016_03 |