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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929561Generated: October 31, 2026

Tert-Butylamine → 5-(tert-Butyl)-3-((tert-butylamino)methyl)-3',4'-dichloro-[1,1'-biphenyl]-2-ol hydrochloride

https://huagongshe.com/reaction/929561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant5-(tert-Butyl)-3',4'-dichloro-2-hydroxy-[1,1'-biphenyl]-3-carbaldehydeHCID 86718723—
Product5-(tert-Butyl)-3-((tert-butylamino)methyl)-3',4'-dichloro-[1,1'-biphenyl]-2-ol hydrochlorideHCID 73776079—

Reaction Steps

5-(tert-Butyl)-3-((tert-butylamino)methyl)-3′,4′-dichloro-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 5-(tert-butyl)-3′,4′-dichloro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296696B2
Source datasetuspto-grants-2016_03
ORD IDord-1f756996ce1645e98e75bad012ffe41c
Source noteuspto-grants-2016_03