Sodium ion → N-(4-bromo-2-chloro-phenyl)-2-{4-[4-(2-hydroxy-ethoxy)-phenyl]-2,5-dioxo-imidazolidin-1-yl}-3-phenyl-butyramide

HRID 92957Notes

Reaction equation

HRID 92957 reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:41])[c:5]([NH:8][C:9]([CH:10]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[N:19]2[C:20](=[O:39])[NH:21][CH:22]([c:25]3[cH:26][cH:27][c:28]([O:31][CH2:32][CH2:33][O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[cH:29][cH:30]3)[C:23]2=[O:24])=[O:40])[cH:6][cH:7]1.[CH3:42][C:43]#[N:44].[CH3:45][Si:46]([Cl:47])([CH3:48])[CH3:49].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[Cl:52][CH2:53][Cl:54].[I-:51].[Na+:50]>>[Br:1][c:2]1[cH:3][c:4]([Cl:41])[c:5]([NH:8][C:9]([CH:10]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[N:19]2[C:20](=[O:39])[NH:21][CH:22]([c:25]3[cH:26][cH:27][c:28]([O:31][CH2:32][CH2:33][OH:34])[cH:29][cH:30]3)[C:23]2=[O:24])=[O:40])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 6397ChlorotrimethylsilaneHCID 8857Ethyl AcetateHCID 30165Iodide IonHCID 68619472N-(4-Bromo-2-chloro-phenyl)-2-{4-[4-(2-tert-butoxy-ethoxy)-phenyl]-2,5-dioxo-imidazolidin-1-yl}-3-phenyl-butyramide

Product 1

HCID 68620084N-(4-bromo-2-chloro-phenyl)-2-{4-[4-(2-hydroxy-ethoxy)-phenyl]-2,5-dioxo-imidazolidin-1-yl}-3-phenyl-butyramide

Sources & evidence

ORD record
ord-c9c11652732e447f93939de02104d61d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…