HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Methylcyclobutyl)amine → 5-(tert-Butyl)-3',4'-dichloro-3-(((1-methylcyclobutyl)amino)methyl)-[1,1'-biphenyl]-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Methylcyclobutyl)amine | HCID 14988399 | — |
| Reactant | 5-(tert-Butyl)-3',4'-dichloro-2-hydroxy-[1,1'-biphenyl]-3-carbaldehyde | HCID 86718723 | — |
| Product | 5-(tert-Butyl)-3',4'-dichloro-3-(((1-methylcyclobutyl)amino)methyl)-[1,1'-biphenyl]-2-ol | HCID 75202066 | — |
Reaction Steps
5-(tert-Butyl)-3′,4′-dichloro-3-(((1-methylcyclobutyl)amino)methyl)-[1,1′-biphenyl]-2-ol was prepared as a white solid using the procedure described in Example 5 from 5-(tert-butyl)-3′,4′-dichloro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde (from Example 19, Step 1) and 1-methylcyclobutylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296696B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c2d2c0d4f6094789a3244631b86d4621 |
| Source note | uspto-grants-2016_03 |