Tert-Butylamine → HCID 86718747, compound

HRID 929581Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:12]=[C:11]([CH:24]=O)[C:10]=2[OH:26])[CH:5]=[CH:6][C:7]=1[Cl:8].[C:27]([NH2:31])([CH3:30])([CH3:29])[CH3:28]>>[ClH:1].[C:27]([NH:31][CH2:24][C:11]1[CH:12]=[C:13]([CH2:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:14]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[C:10]=1[OH:26])([CH3:30])([CH3:29])[CH3:28]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 86718749HCID 86718749, compound

Product 1

HCID 86718747HCID 86718747, compound

Procedure

3-((tert-Butylamino)methyl)-3′,4′-dichloro-5-(3-phenylpropyl)-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 3′,4′-dichloro-2-hydroxy-5-(3-phenylpropyl)-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.

Sources & evidence

ORD record: ord-2cf73aa5aeba4880b35ad958e9d64efe
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09296696B2

Reaction notes

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