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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929908Generated: October 30, 2026

Hydrochloric Acid → HCID 178479239, compound

https://huagongshe.com/reaction/929908

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178453814HCID 178453814—
SolventEthyl AcetateHCID 8857—
ProductHCID 178479239HCID 17847923998%

Reaction Steps

Dissolve (1R,2S,4S,5R,6R)-2-[[-2-(tert-butoxycarbonylamino)acetyl]amino]-4-(4H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid (220 mg, 0.49 mmol) in a saturated solution of hydrogen chloride gas in ethyl acetate (7 mL) and stir at room temperature for 2 hours. Remove the solvent to provide the title compound as a white solid (180 mg, 98%). MS (m/z): 342 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296710B2
Source datasetuspto-grants-2016_03
ORD IDord-9806be84dc2a4d57952a37e10f3779d5
Source noteuspto-grants-2016_03