HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178479239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178453814 | HCID 178453814 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178479239 | HCID 178479239 | 98% |
Reaction Steps
Dissolve (1R,2S,4S,5R,6R)-2-[[-2-(tert-butoxycarbonylamino)acetyl]amino]-4-(4H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid (220 mg, 0.49 mmol) in a saturated solution of hydrogen chloride gas in ethyl acetate (7 mL) and stir at room temperature for 2 hours. Remove the solvent to provide the title compound as a white solid (180 mg, 98%). MS (m/z): 342 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296710B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9806be84dc2a4d57952a37e10f3779d5 |
| Source note | uspto-grants-2016_03 |