反应详情

100 mg (0.26 mmol) of the compound of Example 5 is dissolved in 5 ml of dichloromethane, mixed with 63 mg (0.26 mmol, 70% purity) of meta-chloroperbenzoic acid, and stirred for 4 hours at room temperature. The reaction mixture is separated by means of preparative HPLC (mobile solvent: acetonitrile/water gradient). 97 mg (93% of theory) of the title compound is obtained.

1. customThe reaction mixture is separated by means of preparative HPLC (mobile solvent: acetonitrile/water gradient)