HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidine → [5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-fluoro-3-pyridyl)pyrazol-3-yl]-thiazolidin-3-yl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidine | HCID 10444 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | HCID 89609969 | HCID 89609969 | — |
| Product | [5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-fluoro-3-pyridyl)pyrazol-3-yl]-thiazolidin-3-yl-methanone | HCID 86574607 | — |
Reaction Steps
113 mg (0.25 mmol) of the compound of Example 42A is reacted analogously to the synthesis of the compound of Example 1 with 25 mg (0.28 mmol) of thiazolidine. 91 mg (70% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-4c38bbbf12b749c2b51ba605e0f279c8 |
| Source note | uspto-grants-2016_03 |