HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66687731, compound → 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-methyl-3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66687731 | HCID 66687731 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Bromo-5-trifluoromethoxyphenyl)-1-(6-methylpyridin-3-yl)-1H-pyrazole-3-carboxylic acid | HCID 89602539 | — |
| Product | 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-methyl-3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one | HCID 86574624 | — |
Reaction Steps
50 mg (0.11 mmol) of the compound of Example 41A is reacted analogously to the synthesis of the compound of Example 1 with 15 mg (0.13 mmol) of 4-imidazolinone-hydrochloride. 47 mg (81% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-4d60cff0417e47c097c08f7bdfe6591a |
| Source note | uspto-grants-2016_03 |