HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66687731, compound → 1-[5-[3-Fluoro-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66687731 | HCID 66687731 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Fluoro-5-trifluoromethoxyphenyl)-1-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid | HCID 89602508 | — |
| Product | 1-[5-[3-Fluoro-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one | HCID 86574655 | — |
Reaction Steps
100 mg (0.27 mmol) of the compound of Example 34A is reacted analogously to the synthesis of the compound of Example 1 with 37 mg (0.30 mmol) of 4-imidazolinone-hydrochloride. 98 mg (83% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-059b47663abb4e44be67c07cb3084d47 |
| Source note | uspto-grants-2016_03 |