HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → [5-[3-Fluoro-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazol-3-yl]-morpholino-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Fluoro-5-trifluoromethoxyphenyl)-1-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid | HCID 89602508 | — |
| Product | [5-[3-Fluoro-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazol-3-yl]-morpholino-methanone | HCID 86574669 | — |
Reaction Steps
75 mg (0.20 mmol) of the compound of Example 34A is reacted analogously to the synthesis of the compound of Example 1 with 0.02 ml (0.23 mmol) of morpholine. 80 mg (90% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-2fbae958397e41868621366312f042d5 |
| Source note | uspto-grants-2016_03 |