反应详情

44 mg (0.10 mmol) of the compound of Example 72 is reacted analogously to the synthesis of the compound of Example 6 with 24 mg (0.10 mmol, 70%) of meta-chloroperbenzoic acid overnight at room temperature. The crude product is filtered over a Millipore spray filter and separated by means of preparative HPLC (mobile solvent: acetonitrile/water gradient). 35 mg (77% of theory) of the title compound is obtained.

1. filtrationThe crude product is filtered over a Millipore spray
2. filtrationfilter
3. customseparated by means of preparative HPLC (mobile solvent: acetonitrile/water gradient)