HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazin-2-one → ([5-(3-Bromo-5-methoxyphenyl)-1-(pyridin-3-yl)-1H-pyrazol-3-yl]carbonyl}piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazin-2-one | HCID 231360 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Bromo-5-methoxyphenyl)-1-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid | HCID 89602528 | — |
| Product | ([5-(3-Bromo-5-methoxyphenyl)-1-(pyridin-3-yl)-1H-pyrazol-3-yl]carbonyl}piperazin-2-one | HCID 131735146 | — |
Reaction Steps
50 mg (0.13 mmol) of the compound of Example 50A is reacted analogously to the synthesis of the compound of Example 1 with 15 mg (0.15 mmol) of 2-oxopiperazine. 54 mg (88% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-28b37db8596c4644bd135932ff9371a4 |
| Source note | uspto-grants-2016_03 |