Imidazole → Ethyl 4-((tert-butyldimethylsilyl)oxy)cyclohexanecarboxylate

HRID 93014Notes

Reaction equation

HRID 93014 reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[Si:22]([CH3:23])([CH3:24])[Cl:25].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][CH:9]([OH:12])[CH2:10][CH2:11]1.[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[nH:13]1[cH:14][cH:15][n:16][cH:17]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][CH:9]([O:12][Si:22]([C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:23])[CH3:24])[CH2:10][CH2:11]1

Participants

6

Reactant 5

HCID 795ImidazoleHCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 86973Ethyl 4-hydroxycyclohexanecarboxylate

Product 1

HCID 23144129Ethyl 4-((tert-butyldimethylsilyl)oxy)cyclohexanecarboxylate

Sources & evidence

ORD record
ord-5700f95e35be4cb59f87dc097716cbc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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